Coordonnées
mandy.brecqueville@gmail.com
brecquevillem@ipc.unicancer.fr
Techniques maîtrisées
- extraction ADN/ARN/protéines
- séquençage
- CGH
- transcriptome
- western blot
-culture cellulaire
Doctorat
Intitulé : Pathologie Humaine - Spécialité Oncologie
1ère inscription en thèse :
October 2010
École doctorale :
Sciences de la Vie et de la Santé
Date de soutenance de la thèse :
27 September 2013
Sujet :
Caractérisation moléculaire des syndromes myéloprolifératifs non leucémie myéloide chronique
Directeur de thèse :
Daniel BIRNBAUM
Co-directeur :
Anne MURATI
Unité de recherche :
CRCM - Centre de Recherche en Cancérologie de Marseille
Intitulé de l'équipe :
Oncologie moléculaire
Master
Intitulé : pathologie humaine
June 2010 - La Timone
Langues vivantes
Anglais : Scientifique
Italien : Scolaire
Production scientifique
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Mutations of ASXL1 gene in myeloproliferative neoplasms.
Leukemia
2009
Carbuccia N., Murati A, Trouplin V, Brecqueville M, Adélaïde J, Rey J, Vainchenker W, Bernard O, Chaffanet M, Vey N, Birnbaum D & Mozziconacci MJ.
http://www.nature.com/leu/journal/v23/n11/full/leu2009141a.html
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Rare mutations in DNMT3A in myeloproliferative neoplasms and myelodysplastic syndromes.
Blood Cancer Journal
2011
Brecqueville M, Cervera N, Gelsi-Boyer V, Murati A, Adélaïde J, Chaffanet M, Rey J, Vey N, Mozziconacci MJ & Birnbaum D.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255259/
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Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms.
Blood Cancer Journal
2011
Brecqueville M, Cervera N, Adélaïde J, Rey J, Carbuccia N, Chaffanet M, Mozziconacci MJ, Vey N, Birnbaum D, Gelsi-Boyer V & Murati A.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255245/
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Alterations of polycomb gene BMI1 in human myeloproliferative neoplasms.
Cell Cycle
2012
Brecqueville M, Adélaïde J, Bertucci F, Finetti P, Chaffanet M, & Murati A.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442924/
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Mutation Analysis of ASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12, and TET2 in Myeloproliferative Neoplasms.
Genes, Chromosomes & Cancer
2012
Brecqueville M, Rey J, Bertucci F, Coppin E, Finetti P, Carbuccia N, Cervera N, Gelsi-Boyer V, Arnoulet C, Gisserot O, Verrot D, Slama B, Vey N, Mozziconacci, MJ, Birnbaum D & Murati A.
http://www.ncbi.nlm.nih.gov/pubmed/22489043
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Array comparative genomic hybridization and sequencing
of 23 genes in 80 patients with myelofibrosis at chronic or acute phase.
Haematologica
2013
Brecqueville M, Rey J, Devillier R, Guille A, Gillet R, Adélaide J, Gelsi-Boyer V, Arnoulet C, Chaffanet M, Mozziconacci MJ, Vey N, Birnbaum D & Murati A.
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Myeloid malignancies: mutations, models and management.
BMC Cancer
2012
Murati A, Brecqueville M, Devillier R, Mozziconacci MJ, Gelsi-Boyer V & Birnbaum D.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418560/
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Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.
Journal of hematology & oncology
2012
Gelsi-Boyer V, Brecqueville M, Devillier R, Murati A, Mozziconacci MJ & Birnbaum D
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355025/
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Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts.
Haematologica
2013
Gelsi-Boyer V, Cervera N, Bertucci F, Brecqueville M, Finetti P, Murati A, Arnoulet C, Mozziconacci MJ , Mills K, Vey N & Birnbaum D.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685272/
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Acute myeloid leukemia with myelodysplasia-related changes are characterized by a specific molecular pattern with high frequency of ASXL1 mutations.
American Journal of Hematology
2012
Devillier R, Gelsi-Boyer V, Brecqueville M, Carbuccia N, Murati A, Vey N, Birnbaum D & Mozziconacci MJ.
http://www.ncbi.nlm.nih.gov/pubmed/22535592