Monsieur Nourdine CHAKOURI / PhD

enseignant-chercheur, enseignant du supérieur*Doctorant à l'INSERM U1046

Contact details

Jobs

Comments on availability : néant

Comments on mobility : néant

Availability : 5 2018

Additional information : Cinema, tennis et moto

Mobility : Amérique du nord

Research : OUI

Techniques

Physiology: - Rodent handling and in-vivo animal manipulation, tissue excision, pharmacological treatment - Atrial and ventricular cardiomyocytes isolation using Langendorff system (rat and mouse) - Excitation-contraction coupling study using IonOptix system and study of cardiac contractile apparatus property in permeabilized cardiomyocytes, force measurements and activated force/Ca2+ concentration relationship Molecular biology and histology: - Tissue lysis, western blot, immunoprecipitation, RT PCR, biochemical assays - Histology: cryosections, immunohistochemistry, muscle phenotyping Tools and software: Office Pack, ClampFit, AxioVisio, ImageJ, Odyssey, IonWizard, GraphPad Prism, Origin Pro Lab, data analysis and statistic Languages: English (fluent), French (native language)

PhD

Title : Sciences du Mouvement Humain - MPL

First registration date : 1 October 2014 / 4A

Doctoral school : Sciences du Mouvement Humain

Thesis defense date : 4 April 2018

Subject : Mécanismes physiopathologiques précoces impliqués dans différentes cardiomyopathies induites

Thesis supervisor : MATECKI Stefan

Thesis co-supervisor : CAZORLA Olivier

Research unit : PhyMedExp - Physiologie et Médecine Expérimentale du Coeur et des Muscles

Team : 1. Dynamiques des couplages cardiaques

Master's degree

Title : Master 2 recherche BIOMED

June 2014 - Université de Montpellier 2

Mention : Bien

Publications

  • TRPM4 is involved in excitation-contraction coupling regulation in healthy murine atrial cardiomyocytes
    Archives of Cardiovascular Diseases Supplements, 2015
    Nourdine Chakouri, Melanie Gueffier, Christophe Hedon, Mathieu Granier, Sylvain Richard, Marie Demion
    http://www.sciencedirect.com/science/article/pii/S1878648015300914
  • Transient diastolic dysfunction after prolonged exhaustive exercise: what role for the redox changes of cardiac contractile system?
    Groupe de réflexion sur la recherche cardiovasculaire, 2016
    N. Chakouri, A. Kleindienst, J. Boissière, S. Nottin, S. Gayrard, A. Lacampagne, C. Reboul, O. Cazorla
    http://www.printemps.sfcardio.fr/images/Public/PC16_Programme_imprime-5-avril-2016.pdf
  • The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training
    J Muscle Res Cell Motil, 2017
    Gueffier M, Zintz J, Lambert K, Finan A, Aimond F, Chakouri N, Hédon C, Granier M, Launay P, Thireau J, Richard S, Demion M.
    https://www.ncbi.nlm.nih.gov/pubmed/?term=chakouri
  • Stress-induced protein S-glutathionylation and phosphorylation crosstalk in cardiac sarcomeric proteins - impact on heart function
    International Journal Of Cardiology, 2017
    N. Chakouri, C. Reboul, D. Boulghobra A. Kleindienst, S. Nottin, S. Gayrard, F. Roubille, S. Matecki, A. Lacampagne, O. Cazorla
    https://www.ncbi.nlm.nih.gov/pubmed/29544934
  • The TRPM4 channel is functionally important for the beneficial cardiac remodeling induced by endurance training
    Journal of Muscle Research and Cell Motility, 2017
    Mélanie Gueffier, Justin Zintz, Karen Lambert, Amanda Finan, Franck Aimond, Nourdine Chakouri, Christophe Hédon, Mathieu Granier, Pierre Launay, Jérôme Thireau, Sylvain Richard, Marie Demion

Languages