Madame WENJUN LAN / PhD

Publications

• siRNA-based personalized nanomedicine for cancer treatment
  GIFC-2018, the nineth edition of the Giornate Italo-Francesi di Chimica scientific conference., 2018
  Wenjun Lan, Jingjie Tang, Yifan Jiang, Patricia Santofimia-Castaño, Nelson Dussetti, Juan Iovanna, Ling Peng
  
  
• A Trifluoperazine (TFP)‐derived compound Regulated pancreatic Tumor Progression by Programmed Necrosis
  La XXXIVème réunion du Club Français du Pancréas, 2019
  Lan W, Santofimia-Castaño P, Xia Y, Zhou Z, Huang C, Peng L, Soubeyran P, Velázquez-Campoy A, Abián O, Rizzuti B, Neira JL, Iovanna JL.
  
  
• ZZW-115 sensitizes cancer cells to genotoxic-induced DNA damage by hampering the nuclear translocation of NUPR1
  JCI Insights, 2020
  Lan W, Santofimia-Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S , Camoin L , Huang C , Peng L , Geli V, Velázquez-Campoy A, Abián O, Lomberk G , Urrutia R , Rizzuti B, Soubeyran P, Neira JL, Iovanna JL
  
  
• Targeting NUPR1 with the Small Compound ZZW-115 Is an Efficient Strategy to Treat Hepatocellular Carcinoma
  Cancer Letters, 2020
  Wenjun Lan, Patricia Santofimia, Yi Xia, Zhengwei Zhou, Can Huang, Nicolas Fraunhoffer, Dolores Barea, Melchiore Cervello, Lydia Giannitrapani, Giuseppe Montalto, Ling Peng, Juan Iovanna
  
  
• Flavonoid-Alkylphospholipid Conjugates Elicit Dual Inhibition of Cancer Cell Growth and Lipid Accumulation
  Journal of the Chemical Society, Chemical Communications, 2019
  Zhengwei Zhou, Biyao Luo, Xi Liu, Mimi Chen, Wenjun Lan, Juan L Iovanna, Ling Peng, Yi Xia
  
  
• Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis
  Journal of Clinical Investigation, 2019
  Patricia Santofimia-Castaño, Yi Xia, Wenjun Lan, Zhengwei Zhou, Can Huang, Ling Peng, Philippe Soubeyran, Adrián Velázquez-Campoy, Olga Abián, Bruno Rizzuti, José Neira, Juan Iovanna
  
  
• Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma
  Cells, 2019
  Patricia Santofimia-Castaño, Yi Xia, Ling Peng, Adrián Velázquez-Campoy, Olga Abián, Wenjun Lan, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Philippe Soubeyran, José Luis Neira, Juan Iovanna
  
  
• Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma.
  Cancers, 2019
  Can Huang, Wenjun Lan, Nicolas Fraunhoffer, Analía Meilerman, Juan Iovanna, Patricia Santofimia-Castaño
  
  
• Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis
  Scientific Reports, 2018
  Patricia Santofimia-Castaño, Wenjun Lan, Jennifer Bintz, Odile Gayet, Alice Carrier, Gwen Lomberk, José Luis Neira, Antonio Gonzalez, Raul Urrutia, Philippe Soubeyran, Juan Iovanna
  https://hal-amu.archives-ouvertes.fr/hal-01947729/document
  
• E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments
  Scientific Reports, 2018
  Wenjun Lan, Benjamin Bian, Yi Xia, Samir Dou, Odile Gayet, Martin Bigonnet, Patricia Santofimia-Castaño, Mei Cong, Ling Peng, Nelson Dusetti, Juan Iovanna
  https://hal.archives-ouvertes.fr/hal-01947725/document
  
• Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors
  Proceedings of the National Academy of Sciences of the United States of America, 2018
  Philippe Garrigue, Jingjie Tang, Ling Ding, Ahlem Bouhlel, Aura Tintaru, Erik Laurini, Yuanyuan Huang, Zhenbin Lyu, Mengjie Zhang, Samantha Fernandez, Laure Balasse, Wenjun Lan, Eric Mas, Domenico Marson, Yuhuang Weng, Xiaoxuan Liu, Suzanne Giorgio, Juan Iovanna, Sabrina Pricl, Benjamin Guillet, Ling Peng
  https://hal.archives-ouvertes.fr/hal-01947788/document