Madame Soraya MEZOUAR / PhD


Professional contact details

27, Boulevard Jean Moulin, 13385 MARSEILLE CEDEX 05 , FRANCE

Jobs

Research : NON

Techniques

Culture cellulaire, transfection cellulaire, cytométrie de flux, RT PCR, PCR, isolation de microparticules, western blot, immunofluorescence, test MTT, expérimentation sur le petit animal (souris), injection ectopique, microscopie intravitale,immunohistochimie sur tissus humain, coupe de tissus humain par microtome ou tissus microarray, dissociation tissulaire et culture cellulaire de tumeur primaire, culture de levures, spectrométrie sous UV visible, résonance paramagnétique et électronique, western blot, biologie moléculaire sur bactérie, microbiologie, transformation bactérienne.

PhD

Title : Biologie-Santé - Spécialité Oncologie

First registration date : 1 October 2011 / 4A

Doctoral school : Sciences de la Vie et de la Santé

Thesis defense date : 3 December 2015

Subject : Le rôle des plaquettes dans l'inflammation et la cancer

Thesis supervisor : DUBOIS Christophe

Thesis co-supervisor :

Research unit : VRCM - Vascular Research Center of Marseille

Master's degree

Title : Pathologie Humaine

July 2011 - U2

Mention : Assez bien

Publications

  • On the use of anti-platelet drugs to diminish both tumor growth and thrombosis
    Thrombosis Research, 2012
    R.DARBOUSSET, S. MEZOUAR, R.Bonier, V.Sbarra, D.Farge-Bancel, C.Frère, C.Dubois, L.Panicot-Dubois

  • Tissue factor positive neutrophils bind to injured endothelial wall and initiate thrombus formation
    Blood, 2012
    Roxane Darbousset, Grace M. Thomas, Soraya Mezouar, Corinne Frère, Rénaté Bonier, Nigel Mackman, Thomas Renné, Françoise Dignat-George, Christophe Dubois, and Laurence Panicot-Dubois
    http://bloodjournal.hematologylibrary.org/content/early/2012/07/26/blood-2012-06-437772.abstract
  • P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice.
    Blood, 2014
    Darbousset R, Delierneux C, Mezouar S, Hego A, Lecut C, Guillaumat I, Riederer MA, Evans RJ, Dignat-George F, Panicot-Dubois L, Oury C, Dubois C.

  • Involvement of platelet-derived microparticles in tumor progression and thrombosis.
    Seminar Oncology, 2014
    Mezouar S, Mege D, Darbousset R, Farge D, Debourdeau P, Dignat-George F, Panicot-Dubois L, Dubois C.

  • Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo.
    International Journal of Cancer, 2014
    Mezouar S, Darbousset R, Dignat-George F, Panicot-Dubois L, Dubois C

  • Involvement of neutrophils in thrombus formation in living mice.
    Pathology Biology, 2014
    Darbousset R, Mezouar S, Dignat-George F, Panicot-Dubois L, Dubois C.

  • Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation.
    Blood, 2013
    Darbousset R, Thomas GM, Mezouar S, Frère C, Bonier R, Mackman N, Renné T, Dignat-George F, Dubois C, Panicot-Dubois L.

  • Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the incidence of deep vein thrombosis in mice
    Journal of Thrombosis and Haemostasis, 2015
    Grace Thomas, Alexander Brill, Soraya Mezouar, Lydie Crescence, Maureen Gallant, Christophe Dubois and Denisa Wagner
    http://www.ncbi.nlm.nih.gov/pubmed/25955268
  • Les biomarqueurs de maladies thromboemboliques veineuses chez le patient atteint de cancer
    Oncologie, 2015
    Soraya Mezouar, Roxane Darbousset, Corinne Frère, Dominique Farge-Bancel, Philippe Debourdeau, Françoise Dignat-George, Laurence Panicot-Dubois, and Christophe Dubois

Languages

Anglais : B1 - Intermédiaire

Espagnol : B1 - Intermédiaire